Dues: $15 /yr., payable to Physics Club of New YorkSend to: John Roeder, Secretary-Treasurer17 Honeyflower LaneWest Windsor, NJ 08550-2418
Physics Club of New York
Was established in 1899 and is affiliated with the American Association of Physics Teachers. We hold meetings on selected Friday evenings at Room 207, Silver (formerly Main) Hall at 32 Waverly Place, at New York University
September 13, 2019:
Abba Leffler, Schrödinger, LLC,“Using computer programs as a way to discover drugs and as a hands-on approach for engaging students in a real-world application of chemistry” (in 100 Hayden Hall, Manhattan College)The discovery of a new drug remains one of the most difficult endeavors in chemistry, by some estimatescosting more than a billion dollars and taking longer than a decade from discovery to approval. Computers have the potential to accelerate this process by allowing chemists to visualize how compounds bind to the therapeutic target protein and suggesting ways to improve their drug-like properties.This talk will discuss how the speaker developed a computer program to predict how natural product com-pounds bind to the protein target for smoking cessation therapeutics, an ion channel named the alpha4 beta2 nicotinicacetylcholine receptor. Using this program, the speaker designed four new compounds which were synthesized by solid -phase synthesis, analyzed structurally using NMR spectroscopy, and tested for bioactivity in a fluorescent membrane potential assay. Two of the compounds had significantly improved selectivity relative to the starting compound, a key step in their development into therapeutic agents or tool compounds. This computer algorithm has been freely releasedas an easy-to-use web server called“ToxDock” which has since been used hundreds of times by scientists around the world for their own research questions.The talk will close by describing the speaker’s educational and career path from a specialized science highschool to obtaining an industry position and will point out emerging opportunities for chemistry teachers to integrate hands-on molecular modeling technology into their classrooms to get students engaged in a real-world application ofchemistry, drug discovery.October 18, 2019:Demo Derby I
November 22, 2019:
Marco Machado, NYC Board of Education, American Museum of Natural History, and The New School, “STEM Instruction in the Pop Culture Classroom”STEM instruction has seen graphic representations be used alongside text to improve student comprehension and retention for decades. With the rising popularity of comics, manga, and graphic novels in pop culture, an opportunity to further engage students by combining this pedagogical strategy with characters and themes students are familiar with has presented itself in the science classroom. Come see specific examples of how new media can be used to improve student interest, assessment variety, and content literacy, as well as learn about some of the best comics and graphic novels for teaching physics.
December 13, 2019:
Robert P. Crease, Department of Philosophy, Stony Brook University,“What Ten Thinkers Can Teach us about Science and Authority”Professor Crease will discuss how Francis Bacon, Galileo Galilei, and others at the beginnings ofmodern science made a case for its worldly authority, the resistance they encountered, and how they responded. These stories are uncannily relevant to science denial today and how to address it. This should bea very informative and enjoyable evening for us all.
January 24, 2020:
Lew Malchick, Brooklyn Polytechnic High School (ret.),“Discussion of Laboratory Safety” (in room E/F, 2nd floor, UFT Headquarters, 50 Broadway)
February 28, 2020:
Professor Joshua Ruderman, New York University, “Dark Matter Genesis: Tales from an Agnostic”We believe that most of the matter in our Universe is dark matter. We don’t know what dark matter is, and we don’t know where it came from. But the challenge is not that we don’t know how to explain dark matter. It’s that we have multiple possible explanations and we don’t know which among them is correct-- if any. I will tell several “stories” of howdark matter may have been produced during the Big Bang and the challenges of testing these storiesMarch 27, 2020:Michael Victor Danza, Kingsborough Community College, “3D Design & 3D Printing Simplified” You will learn 3D Design and 3DPrototyping using the new manufacturing technology such as 3D Printing as applied to your Project-Based Learning in science, math, and engineering classes.t.April 24, 2020:Demo Derby IIIn the event of inclement weather, call Secretary-Treasurer John Roeder at The Calhoun School, (212)-497-6500, to ascertain the status of the meeting. Unless specified otherwise, meetings are held in Room 207 of Silver Hall, 32 Waverly Place, New York University, at 7:15 p.m. All meetings are preceded by a pre-meeting dinner at a local restaurant announced in the monthly meeting notices. The Physics Club of New York is a member organization of the Science Council Of New York City and an affiliate of the AmericanAssociation of Physics Teachers.Download the September Notes
For those history buffs, here is a link to a copy of an 1899 article in the Sciencenewsletter announcing the Physics Club of New York
Physics Club of New York 2019-2020 Season Schedule: